Tweens are nice to make linear movements (not only ofc) but am not sure you can do it with frame by frame, but you can for example draw the animation of your Tilemap frame by frame and add (draw) a tween on it, I have a WiP example for tween movements looking like chess that uses the easystartjs framework on my GitHub Account (but with a fixed Tilemap not animated maybe a good way for developping my game)
Think that tweens are for moving (for example) and animations is not a mouvement if you let the sprite as it is without handling it with inputs